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Jacked (Jack3d) - Buy One, Get One Half Price!
Product Description
USPlabs Jack3d
FORMULA BREAKDOWN
Schizandrol A
This compound is an exciting one...
It has not only been shown to outperform amphetamine in cognitive tasks involving focus, but it has also been shown to greatly increase the capacity of muscles to perform work,while also increasing physical force. In essence, it is able to provide a stimulating effect to the body and mind [1].
Last, but certainly not least; unlike various stimulants which can increase catabolic hormone levels (i.e. glucocorticoids), this compound has been shown to lower levels of hormones like cortisol in animal models [2].
And, as we all know, cortisol is dramatically increased during a workout and can stop muscle growth in its tracks.
Schizandrol A will help keep cortisol at bay so you can get bigger, stronger & leaner!
Don't get confused with the cheap, ineffective Shizandra found in some other products. Our Schizandrol A is a potent Engineered Extract only found in USPlabs Jack3d.
Caffeine
Caffeine belongs to the family of methylxanthine compounds. It's able to stimulate the CNS, while also stimulating contractility of skeletal muscle directly and this may partially be due to the release of catecholamines such as norepinephrine.
Caffeine has the benefit of fighting fatigue and drowsiness; enhancing the flow of thoughts; increasing alertness and improving intellectual efforts along with producing euphoria or a sense of well-being in some cases. Just as these methylxanthines can increase the effectiveness of compounds such as ephedrine, it is thought that it may do the same for the unique compound found in Geranium [3-6].
In terms of specifics, at the cortical level, caffeine is also thought to promote increased wakefulness or vigilance, via adenosine receptor antagonism, causing stimulation of cholinergic neurons in the basal forebrain and reinforcing inhibition exerted upon sleep-promoting GABA neurons. The stimulant effects are exerted directly upon the cerebral cortex, medulla oblongata, and spinal cord.
...Most formulas just throw in a ton of caffeine and hope for the best.
USPlabs Jack3d has a precise blend of compounds that will not only get you flying through your workouts like a mad man, but will allow you to have hours upon hours of energy without a harsh crash at the end...
Jack3d's ingredients are perfectly blended for a powerful synergistic effect...
This is one area where USPlabs Jack3d truly separates itself. It's not just a ton of caffeine thrown in so you can "feel it." It's the proper stimulants in the proper dosages.
Beta-alanine
Beta-alanine serves as the rate-limiting precursor of carnosine and as such, it has been shown that by supplementing with beta-alanine, you can greatly increase carnosine levels in skeletal muscle tissue.
Carnosine is an extremely important dipeptide that is generally present in rather high concentrations in skeletal muscle, though it is also found in nervous tissue and other excitable tissues as well [12,13].
It is so important because it acts as a buffer of sorts, preventing the increase of acidity or Hydrogen ion accumulation in skeletal muscle; something which is thought to contribute to the fatiguing of muscles.
In short, you are able to delay fatigue; allowing you to lift for longer periods.
It is no coincidence that the most explosive athletes (e.g. sprinters) in the world have higher carnosine levels in their muscles. Looking to the animals of our world provides us with yet another example; the most explosive animals such as greyhounds and thoroughbred horses also have the highest level of carnosine in their muscle tissue as well.
Creatine Monohydrate
While we may negate the increase in Hydrogen ion levels in skeletal muscle by increasing carnosine levels, we still must overcome one more obstacle in order to allow us to prevent fatigue while working out. In this case, we must use a compound which can ultimately increase the adenosine triphosphate (ATP) levels in muscle. ATP, as we all know, is a high energy nucleotide which acts as the major energy carrying molecule in our bodies.
Consequently, muscle fatigue is also related to energy loss in skeletal muscle, specifically, ATP being converted to adenosine diphosphate (ADP). In effect, one phosphate group is lost and must be replenished in order for the muscle cell to continue on working.
By supplementing with creatine, we are able to increase the levels of phosphocreatine in muscle. Phosphocreatine is a high energy buffering compound which is able to donate a phosphate group to ADP, allowing the formation of ATP once again. In short, we can prevent or reduce fatigue from occurring by increasing phosphocreatine levels, which in turn will allow for the regeneration of ATP from ADP.
By addressing both the regeneration of ATP, while also limiting Hydrogen ion accumulation, we are able to provide a one-two combination that effectively reduces fatigue to an amazing degree.
If this weren't enough, the compound we have included may also increase the swelling of muscle cells, possibly increasing protein synthesis or inhibiting catabolism; the end result being an increase in muscle mass.
While creatine monohydrate isn't new or ground-breaking, it's scientifically sound, proven millions of times over in the real-world and an absolute must in any pre-workout formula [8-11].
The "Best" Creatine?
It seems there have been a myriad of creatine products on the market in recent years; each and every one of them claim to improve upon the original creatine monohydrate. Yet, not one of them has ever been able to do so. Though, should this really be a surprise?
It has been known for some time now that creatine monohydrate's bioavailability is nearly 100%, despite many marketing attempts to make you believe otherwise.
Yet, each one of these products has claimed that they could improve the product in some way.
The only reason for the stomach issues associated with creatine was the loading phase that was promoted when creatine first came out. This has since been disproven & NOT needed to achieve desired results...
First it was the effervescent formulations, claiming that the buffered product could resist acidic degradation of creatine to creatinine in the stomach, while at the same time, decreasing the transit time for the creatine to enter the small intestine from the stomach, again, hypothetically reducing the amount of creatine degradation.
Last, it was supposed to improve solubility of the creatine in solution, hypothetically resulting in improved absorption. Yet, scientific studies showed no improvement in absorption or bioavailability with these formulations.
The next attempt was to improve creatine absorption with various salts, the latest of which appear to be tri-creatine citrate and creatine pyruvate. Yet again, as you would expect, studies have shown no significant increase in bioavailability over regular creatine monohydrate.
Don't be fooled by slick marketing; some manufacturers may cite a study which had shown slightly greater (although not statistically significant and hence not accepted as likely being unique) plasma concentrations of creatine with the pyruvate salt in particular.
However, they will most certainly and conveniently leave out the scientists' own conclusions, "The higher plasma concentration with Creatine Pyruvate is unlikely to have been due to greater bioavailability, since the bioavailability of Creatine Monohydrate is known to be close to 100%" and "It is questionable if the small differences observed in the plasma concentrations with the three treatments would have any effect on the increase in creatine in muscle."
Yet another example of these futile attempts includes the creatine ethyl ester. This particular product also boasted claims of improved bioavailability by preventing the degradation of creatine to creatinine in the stomach, while also improving physiochemical properties conducive of improved bioavailability.
Yet again, the product failed to do so. In fact, not only did the addition of the ethyl ester not help, it actually was shown to accelerate the degradation of creatine to creatinine in an acidic solution. It can be estimated from such studies that the bioavailability of the creatine ethyl ester is actually far less than regular creatine monohydrate, which again, is already nearly 100% to begin with.
Perhaps other manufacturers will finally get the hint that creatine monohydrate isn't going to be improved upon as there is virtually no room for improvement. Yet, that won't stop them as history has shown.
Creatine monohydrate after all is an effective product. In fact, it's probably one of, if not the most scientifically validated dietary supplement in existence and it delivers real world results as well.
But remember, the marketing arm of these companies are banking on the fact that creatine is such a great supplement; a supplement that has become a staple for nearly all athletes and weightlifters, that they want to create their own unique version, touting some supposed added benefits. But as you've learned, there is no such thing.
FORMULA BREAKDOWN
Schizandrol A
This compound is an exciting one...
It has not only been shown to outperform amphetamine in cognitive tasks involving focus, but it has also been shown to greatly increase the capacity of muscles to perform work,while also increasing physical force. In essence, it is able to provide a stimulating effect to the body and mind [1].
Last, but certainly not least; unlike various stimulants which can increase catabolic hormone levels (i.e. glucocorticoids), this compound has been shown to lower levels of hormones like cortisol in animal models [2].
And, as we all know, cortisol is dramatically increased during a workout and can stop muscle growth in its tracks.
Schizandrol A will help keep cortisol at bay so you can get bigger, stronger & leaner!
Don't get confused with the cheap, ineffective Shizandra found in some other products. Our Schizandrol A is a potent Engineered Extract only found in USPlabs Jack3d.
Caffeine
Caffeine belongs to the family of methylxanthine compounds. It's able to stimulate the CNS, while also stimulating contractility of skeletal muscle directly and this may partially be due to the release of catecholamines such as norepinephrine.
Caffeine has the benefit of fighting fatigue and drowsiness; enhancing the flow of thoughts; increasing alertness and improving intellectual efforts along with producing euphoria or a sense of well-being in some cases. Just as these methylxanthines can increase the effectiveness of compounds such as ephedrine, it is thought that it may do the same for the unique compound found in Geranium [3-6].
In terms of specifics, at the cortical level, caffeine is also thought to promote increased wakefulness or vigilance, via adenosine receptor antagonism, causing stimulation of cholinergic neurons in the basal forebrain and reinforcing inhibition exerted upon sleep-promoting GABA neurons. The stimulant effects are exerted directly upon the cerebral cortex, medulla oblongata, and spinal cord.
...Most formulas just throw in a ton of caffeine and hope for the best.
USPlabs Jack3d has a precise blend of compounds that will not only get you flying through your workouts like a mad man, but will allow you to have hours upon hours of energy without a harsh crash at the end...
Jack3d's ingredients are perfectly blended for a powerful synergistic effect...
This is one area where USPlabs Jack3d truly separates itself. It's not just a ton of caffeine thrown in so you can "feel it." It's the proper stimulants in the proper dosages.
Beta-alanine
Beta-alanine serves as the rate-limiting precursor of carnosine and as such, it has been shown that by supplementing with beta-alanine, you can greatly increase carnosine levels in skeletal muscle tissue.
Carnosine is an extremely important dipeptide that is generally present in rather high concentrations in skeletal muscle, though it is also found in nervous tissue and other excitable tissues as well [12,13].
It is so important because it acts as a buffer of sorts, preventing the increase of acidity or Hydrogen ion accumulation in skeletal muscle; something which is thought to contribute to the fatiguing of muscles.
In short, you are able to delay fatigue; allowing you to lift for longer periods.
It is no coincidence that the most explosive athletes (e.g. sprinters) in the world have higher carnosine levels in their muscles. Looking to the animals of our world provides us with yet another example; the most explosive animals such as greyhounds and thoroughbred horses also have the highest level of carnosine in their muscle tissue as well.
Creatine Monohydrate
While we may negate the increase in Hydrogen ion levels in skeletal muscle by increasing carnosine levels, we still must overcome one more obstacle in order to allow us to prevent fatigue while working out. In this case, we must use a compound which can ultimately increase the adenosine triphosphate (ATP) levels in muscle. ATP, as we all know, is a high energy nucleotide which acts as the major energy carrying molecule in our bodies.
Consequently, muscle fatigue is also related to energy loss in skeletal muscle, specifically, ATP being converted to adenosine diphosphate (ADP). In effect, one phosphate group is lost and must be replenished in order for the muscle cell to continue on working.
By supplementing with creatine, we are able to increase the levels of phosphocreatine in muscle. Phosphocreatine is a high energy buffering compound which is able to donate a phosphate group to ADP, allowing the formation of ATP once again. In short, we can prevent or reduce fatigue from occurring by increasing phosphocreatine levels, which in turn will allow for the regeneration of ATP from ADP.
By addressing both the regeneration of ATP, while also limiting Hydrogen ion accumulation, we are able to provide a one-two combination that effectively reduces fatigue to an amazing degree.
If this weren't enough, the compound we have included may also increase the swelling of muscle cells, possibly increasing protein synthesis or inhibiting catabolism; the end result being an increase in muscle mass.
While creatine monohydrate isn't new or ground-breaking, it's scientifically sound, proven millions of times over in the real-world and an absolute must in any pre-workout formula [8-11].
The "Best" Creatine?
It seems there have been a myriad of creatine products on the market in recent years; each and every one of them claim to improve upon the original creatine monohydrate. Yet, not one of them has ever been able to do so. Though, should this really be a surprise?
It has been known for some time now that creatine monohydrate's bioavailability is nearly 100%, despite many marketing attempts to make you believe otherwise.
Yet, each one of these products has claimed that they could improve the product in some way.
The only reason for the stomach issues associated with creatine was the loading phase that was promoted when creatine first came out. This has since been disproven & NOT needed to achieve desired results...
First it was the effervescent formulations, claiming that the buffered product could resist acidic degradation of creatine to creatinine in the stomach, while at the same time, decreasing the transit time for the creatine to enter the small intestine from the stomach, again, hypothetically reducing the amount of creatine degradation.
Last, it was supposed to improve solubility of the creatine in solution, hypothetically resulting in improved absorption. Yet, scientific studies showed no improvement in absorption or bioavailability with these formulations.
The next attempt was to improve creatine absorption with various salts, the latest of which appear to be tri-creatine citrate and creatine pyruvate. Yet again, as you would expect, studies have shown no significant increase in bioavailability over regular creatine monohydrate.
Don't be fooled by slick marketing; some manufacturers may cite a study which had shown slightly greater (although not statistically significant and hence not accepted as likely being unique) plasma concentrations of creatine with the pyruvate salt in particular.
However, they will most certainly and conveniently leave out the scientists' own conclusions, "The higher plasma concentration with Creatine Pyruvate is unlikely to have been due to greater bioavailability, since the bioavailability of Creatine Monohydrate is known to be close to 100%" and "It is questionable if the small differences observed in the plasma concentrations with the three treatments would have any effect on the increase in creatine in muscle."
Yet another example of these futile attempts includes the creatine ethyl ester. This particular product also boasted claims of improved bioavailability by preventing the degradation of creatine to creatinine in the stomach, while also improving physiochemical properties conducive of improved bioavailability.
Yet again, the product failed to do so. In fact, not only did the addition of the ethyl ester not help, it actually was shown to accelerate the degradation of creatine to creatinine in an acidic solution. It can be estimated from such studies that the bioavailability of the creatine ethyl ester is actually far less than regular creatine monohydrate, which again, is already nearly 100% to begin with.
Perhaps other manufacturers will finally get the hint that creatine monohydrate isn't going to be improved upon as there is virtually no room for improvement. Yet, that won't stop them as history has shown.
Creatine monohydrate after all is an effective product. In fact, it's probably one of, if not the most scientifically validated dietary supplement in existence and it delivers real world results as well.
But remember, the marketing arm of these companies are banking on the fact that creatine is such a great supplement; a supplement that has become a staple for nearly all athletes and weightlifters, that they want to create their own unique version, touting some supposed added benefits. But as you've learned, there is no such thing.
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